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Sildenafil is a potent and selective inhibitor of cGMP-specific phosphodiesterase type 5 (PDE5), which is responsible for degradation of cGMP in the corpus cavernosum.

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For questions regarding pricing and availability of products from Canada Drugs you may call 1-800-226-3784.Concomitant use of soluble guanylyl cyclase stimulators, such as riociguat.

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Order shop, no prescription online pharmacy sildenafil, generic soft, the cost.In the United States, Pfizer received two patents for sildenafil: one for its indication to treat cardiovascular disease (marketed as Revatio) and another for its indication to treat erectile dysfunction (marketed as Viagra).Psychostimulants (e.g., amphetamines, cocaine, methylphenidate ).Care should be exercised by people who are also taking protease inhibitors for the treatment of HIV infection.It was initially studied for use in hypertension (high blood pressure) and angina pectoris (a symptom of ischaemic heart disease ).What links here Related changes Upload file Special pages Permanent link Page information Wikidata item Cite this page.Medications used in the management of pulmonary arterial hypertension ( B01, C02 ).

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The patent on Revatio (indicated for pulmonary arterial hypertension rather than erectile dysfunction) expired in late 2012.Sildenafil Citrate Pills Uk a profitable business demands much more than good business sense.

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Professional athletes have been documented using sildenafil, believing the opening of their blood vessels will enrich their muscles.

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Call Centre (sales, refill and order information): 24 hours, 7 days a week.Sildenafil is broken down in the liver by hepatic metabolism using cytochrome p450 enzymes, mainly CYP450 3A4(major route), but also by CYP2C9 (minor route) hepatic isoenzymes.