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Sildenafil acts by inhibiting cGMP-specific phosphodiesterase type 5 (phosphodiesterase 5, PDE 5 ), an enzyme that promotes degradation of cGMP, which regulates blood flow in the penis.Viagra Super Active In Uk Viagra Super Active Shipped From Canada.

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This metabolite also has an affinity for the PDE receptors, about 40% of that of sildenafil.

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Rare but serious side effects include prolonged erections, which can lead to damage to the penis, and sudden-onset hearing loss.There are also mouth spray preparations of sildenafil for faster onset of action.

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Sildenafil is a potent and selective inhibitor of cGMP-specific phosphodiesterase type 5 (PDE5), which is responsible for degradation of cGMP in the corpus cavernosum.

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